MANE Group, one of the world’s leading flavor and fragrance manufacturers, and Arzeda Corp., a pioneer in AI-driven protein design, have entered the next phase of their strategic partnership. Under the new agreement, MANE has an exclusive global license to produce and commercialize Arzeda’s groundbreaking ViaLeaf™ Reb-M stevia, a revolutionary process that uses Nobel Prize-winning technology.
• Complete Reb-M value chain
The license enables MANE to manage the entire Reb-M value chain, from production through commercialization. This strategic milestone builds on the successful collaboration between MANE and Arzeda announced in March 2026, and significantly advances the companies’ shared goal of making high-quality, natural sugar-reduction solutions more accessible to the global food and beverage industry.
• Computational protein-designed sweetener delivers innovative, high-performance solutions
“This new step in our partnership with Arzeda reflects our commitment to delivering innovative, high-performance solutions,” says Samantha Mane, CEO of the MANE Group. “By combining Arzeda’s breakthrough technology with MANE’s production, flavor creation, application and commercial expertise, we can now offer the market a fully integrated Reb-M solution that delivers outstanding flavor and competitive economics.” The expanded partnership will help food and beverage manufacturers meet growing consumer demand for lower-sugar products while maintaining flavor and supporting clean-label development, setting a new benchmark for natural sweetening solutions.
• In-demand steviol glycoside delivers clean sweetness
Reb M is widely recognized as the most desirable steviol glycoside for its clean, sugar-like sweetness and neutral flavor profile. Arzeda’s proprietary innovative protein design technology has transformed the economics of Reb-M production, and MANE’s formulation and commercial capabilities, global manufacturing and industrial expertise will enable a scalable Reb-M solution and large-scale deployment to meet growing market demand for natural sugar-reduction solutions. Customers will benefit from superior flavor performance, reliable supply, and an exceptional quality-to-cost ratio.
• Trusted partners, trusted ingredients
“MANE is uniquely positioned to unlock the full potential of ViaLeaf Reb-M, the first-ever product
enabled by AI-driven protein design to reach the market,” says Alexandre Zanghellini, PhD, CEO of Arzeda. “By entrusting MANE with production and commercialization, we are combining Arzeda’s innovation capabilities with MANE’s global scale and industry leadership to accelerate the adoption of next-generation sweetening solutions worldwide.”